A correction formula for neuron‑specific enolase measurement in hemolyzed neonatal serum samples

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Hemolysis correction factor in the measurement of serum neuron-specific enolase.

Neuron-specific enolase (NSE) is comprised of two isoforms, ag and gg, of the glycolytic enzyme enolase. It is present almost exclusively in neurons and neuroendocrine tissues (1–3). The protein is a valuable tumor marker for monitoring the outcome and disease course in patients with cancer of the neuroendocrine type, in particular small cell lung cancer and neuroblastoma (4, 5). In addition, t...

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Qualitative and Quantitative Approaches for Determination of Hemolyzed Serum

Abstract Background and Objective: Prevention of medical laboratory errors is a major goal of quality control programs. Hemolyzed specimen is one of the common issues causing medical laboratory errors. Apart from the visual assessment, the measurement of serum hemoglobin concentration can be another method to evaluate the intensity of hemolysis. We aimed to assess hemolyzed serum s...

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ژورنال

عنوان ژورنال: Biomedical Reports

سال: 2018

ISSN: 2049-9434,2049-9442

DOI: 10.3892/br.2018.1081